the aim was to study the peculiarities of differential diagnosis, prevention and treatment of different forms of rhinitis in kazakhstan children and adolescents.124 children and adolescents aged 1-17 years were randomly enrolled in our hospital based study in 2010 and 2011. skin prick tests and total serum ige level were assessed in all allergic patients. subcutaneous specific immunotherapy was...

Background Effective treatment requires a correct diagnosis, however for different subgroups of chronic rhinitis patients differentiation on a clinical level is complicated. In the case of non-allergic rhinitis (NAR) that represents a wide spectrum of diseases, we are also faced with a missing mechanistic or molecular diagnosis. Here we present an unbiased transcriptomic approach on nasal epith...

Pattern, or "zheng," differentiation is the essential guide to treatment with traditional Chinese medicine (TCM). However, the considerable variability between TCM patterns complicates evaluations of TCM treatment effectiveness. The aim of this study was to explore and characterize the relationship between patterns and the core patterns of allergic rhinitis. We summarized 23 clinical trials of ...

The main objective of this study is to analyze the effects sublingual specific immunotherapy and conventional drug therapy on inflammatory factors immune function in children with allergic rhinitis. research subjects were divided into three groups, group A received administration dust mite drops, B routine treatment such as passive intervention topical hormones, antihistamines nasal irrigation ...

In two in vitro studies, we examined the immunological (pathways of the) effects of Citrus/Cydonia comp. from, respectively, a healthy and an allergic donor; peripheral blood mononuclear cells (PBMCs) were isolated out of peripheral blood and analyzed in vitro after polyclonal stimulation of T-cells. The differentiation capacity and the influence with regard to Th1 (IFN-gamma) and Th2 (IL-5) ce...

BACKGROUND TIM-1, a member of the T cell immunoglobulin and mucin (TIM) domain family, is involved in T-cell differentiation and has been implicated in allergic diseases. An association between TIM-1 and allergic rhinitis, however, has not been established. OBJECTIVE To investigate whether TIM-1 gene polymorphisms were associated with allergic rhinitis in a Han Chinese population. METHODS T...

Background: Chronic rhinitis in children is a common problem. Investigation to diagnose allergic (AR) using skin prick test for aeroallergens requires specialist doctor, which not simply performed primary health care facilities. Therefore, diagnosing patients with AR and non-allergic (NAR) based on clinical symptoms essential treatment planning. This study compared between NAR, comorbidities, d...

PURPOSE OF REVIEW To discuss the role of vitamin D in chronic rhinitis and chronic rhinosinusitis (CRS). RECENT FINDINGS Vitamin D has been shown to have an immunomodulatory effect with a significant impact on immune function. Specifically, vitamin D regulates the mechanisms which suppress the inflammatory response and direct the differentiation fate of immune cells. Vitamin D has been shown ...

Modified epithelial cell distribution in chronic airways inflammation. C. Chapelin, A. Coste, L. Gilain, F. Poron, F. Verra, E. Escudier. ERS Journals Ltd 1996. ABSTRACT: Although airway epithelium is known to be modified during chronic respiratory diseases, epithelial cells have rarely been precisely quantified. We therefore intended to evaluate epithelial cell distribution in inflammatory ai...